Metadoxine

Metadoxine blocks adipocyte differentiation in association with inhibition of the protein kinase A-cAMP response element binding protein (PKA-CREB) pathway.

Product Specifications

CAS Number

[74536-44-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

PKA

Type

Reference compound

Related Pathways

Stem Cell/Wnt; TGF-beta/Smad

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Metadoxine.html

Purity

99.88

Solubility

H2O : ≥ 155 mg/mL

Smiles

O=C(O)[C@H](CC1)NC1=O.OCC2=C(CO)C(O)=C(C)N=C2

Molecular Formula

C13H18N2O6

Molecular Weight

298.29

Precautions

H302, H315, H319, H335

References & Citations

[1]Yang YM, et al. Metadoxine, an ion-pair of pyridoxine and L-2-pyrrolidone-5-carboxylate, blocks adipocyte differentiation in association with inhibition of the PKA-CREB pathway. Arch Biochem Biophys. 2009 Aug 15;488 (2) :91-9.