ARV-393
ARV-393 is a potent, orally bioavailable PROTAC molecule that induces the ubiquitination and proteasomal degradation of BCL6. It is utilized in research for studying BCL6 biology and has demonstrated activity in preclinical models of diffuse large B-cell lymphoma (DLBCL) and other non-Hodgkin's lymphomas.
Product Specifications
CAS Number
2851885-95-3
Product Name Alternative
ARV393
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
99.96% (May vary between batches)
Solubility
DMSO:8 mg/mL (8.9 mM)
Smiles
FC1=C2C (C (=O) N (C2) C3C (=O) NC (=O) CC3) =CC=C1C4CCN (CC4) [C@@H]5C[C@@H] (OC6CCN (CC6) C=7N=C (NC=8C=C9C (=CC8) N (C (C) C) C (=O) C (OCC (NC) =O) =C9) C (Cl) =CN7) C5
Molecular Formula
C46H53ClFN9O7
Molecular Weight
898.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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