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ARV-393

ARV-393 is a potent, orally bioavailable PROTAC molecule that induces the ubiquitination and proteasomal degradation of BCL6. It is utilized in research for studying BCL6 biology and has demonstrated activity in preclinical models of diffuse large B-cell lymphoma (DLBCL) and other non-Hodgkin's lymphomas.

Product Specifications

CAS Number

2851885-95-3

Product Name Alternative

ARV393

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery

Purity

99.96% (May vary between batches)

Solubility

DMSO:8 mg/mL (8.9 mM)

Smiles

FC1=C2C (C (=O) N (C2) C3C (=O) NC (=O) CC3) =CC=C1C4CCN (CC4) [C@@H]5C[C@@H] (OC6CCN (CC6) C=7N=C (NC=8C=C9C (=CC8) N (C (C) C) C (=O) C (OCC (NC) =O) =C9) C (Cl) =CN7) C5

Molecular Formula

C46H53ClFN9O7

Molecular Weight

898.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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