Tertiapin (reduced)
Product Specifications
UNSPSC Description
Tertiapin (reduced) is a kind of synthesis of melittin, its Cys3-Cys14 and Cys5-Cys18 between containing a disulfide bond. Tertiapin (reduced) is a kind of inward rectifier potassium channels blockers, can block the activity of calcium activates large conductance potassium channels. Tertiapin (reduced) can be used for research in diseases such as rheumatoid arthritis and multiple sclerosis[1].
Target Antigen
Potassium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tertiapin-reduced.html
Smiles
NCCCC[C@@H](C(N)=O)NC([C@H](CCCCN)NC(CNC([C@H](CS)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@@H](NC([C@H](CS)NC([C@H](CCSC)NC([C@H](CC1=CN=CN1)NC([C@H]2N(CCC2)C([C@H]([C@@H](C)CC)NC([C@H]([C@@H](C)CC)NC([C@H]([C@@H](C)CC)NC([C@H](CCCNC(N)=N)NC([C@H](CC(N)=O)NC([C@H](CS)NC([C@H](CC(N)=O)NC([C@H](CS)NC([C@H](CC(C)C)NC([C@@H](N)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CNC4=CC=CC=C34)=O)=O)=O)=O)=O)=O
Molecular Weight
2459.10
References & Citations
[1]Kitamura H, et al. Tertiapin potently and selectively blocks muscarinic K+ channels in rabbit cardiac myocytes[J]. Journal of Pharmacology and Experimental Therapeutics, 2000, 293(1): 196-205.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P2791/Tertiapin-reduced-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P2791/
Clinical Information
No Development Reported
CAS Number
58694-52-3
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