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NMDAR/TRPM4-IN-2

NMDAR/TRPM4-IN-2 (compound 8) is a potent NMDAR/TRPM4 interaction interface inhibitor. NMDAR/TRPM4-IN-2 shows neuroprotective activity. NMDAR/TRPM4-IN-2 prevents NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons, with an IC50 of 2.1 μM. NMDAR/TRPM4-IN-2 protects mice from MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss.

Product Specifications

CAS Number

2243506-33-2

Field of Research

Neuroscience; Cell Biology

Purity

>98%

Smiles

C (C1C=CC=C (Br) C=1) N (CC) CCN.Cl

Molecular Formula

C11H18BRCLN2

Molecular Weight

293.631021022797

Notes

For research use only.

Available Sizes

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