NMDAR/TRPM4-IN-2
NMDAR/TRPM4-IN-2 (compound 8) is a potent NMDAR/TRPM4 interaction interface inhibitor. NMDAR/TRPM4-IN-2 shows neuroprotective activity. NMDAR/TRPM4-IN-2 prevents NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons, with an IC50 of 2.1 μM. NMDAR/TRPM4-IN-2 protects mice from MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss.
Product Specifications
CAS Number
2243506-33-2
Field of Research
Neuroscience; Cell Biology
Purity
>98%
Smiles
C (C1C=CC=C (Br) C=1) N (CC) CCN.Cl
Molecular Formula
C11H18BRCLN2
Molecular Weight
293.631021022797
Notes
For research use only.
Available Sizes
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