HaloPROTAC-E
HaloPROTAC-E is a novel HaloPROTAC potent degrader, inducing reversible degradation of two endosomally localized proteins, SGK3 and VPS34, with a DC50 of 3-10 nM, remarkably selective inducing only degradation of the Halo tagged endogenous VPS34 complex (VPS34, VPS15, Beclin1, and ATG14) and no other proteins were significantly degraded.
Product Specifications
CAS Number
2365478-58-4
Purity
>98%
Smiles
C (C1 (CC1) C#N) (=O) N[C@@H] (C (C) (C) C) C (N1C[C@H] (O) C[C@H]1C (=O) NCC1C=CC (C2SC=NC=2C) =CC=1OCCOCCOCCOCCCCCCCl) =O
Molecular Formula
C39H56CLN5O8S
Molecular Weight
790.408648490906
Notes
For research use only.
Available Sizes
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