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BRD 4354 ditrifluoroacetate

BRD 4354 ditrifluoroacetate is a selective class IIa histone deacetylase (HDAC) inhibitor, demonstrating moderate potency against HDAC5 and HDAC9 with IC50 values of 0.85 μM and 1.88 μM, respectively. This compound is a valuable chemical probe for epigenetic research, utilized in both in vitro and in vivo studies to investigate the roles of HDAC5/9 in cardiac development, neuronal function, and muscle differentiation.

Product Specifications

Field of Research

Epigenetics & Chromatin, Molecular Biology

Smiles

OC1=C2N=CC=CC2=C (Cl) C=C1C (N3CCN (CC) CC3) C4=CC=CN=C4.O=C (O) C (F) (F) F.O=C (O) C (F) (F) F

Molecular Formula

C25H25ClF6N4O5

Molecular Weight

610.93

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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