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Neriifolin

Neriifolin is a cardiac glycoside and Na+/K+-ATPase inhibitor derived from Cerbera manghas. It exhibits anticancer properties by inducing cell cycle arrest and apoptosis in vitro in leukemia (THP-1) and liver cancer (HepG2) cell lines, and is also used in prostate cancer research.

Product Specifications

CAS Number

466-07-9

Product Name Alternative

NSC 123976, NSC123976, Na+/K+ ATPase, Autophagy, Apoptosis, 17β-Neriifolin, 17beta-Neriifolin

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Purity

98.59% (May vary between batches)

Solubility

DMSO:80 mg/mL (149.62 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.17 mM)

Smiles

O[C@@]12[C@]3 ([C@@] ([C@]4 (C) [C@] (CC3) (C[C@@H] (O[C@H]5[C@@H] (O) [C@H] (OC) [C@@H] (O) [C@H] (C) O5) CC4) [H]) (CC[C@]1 (C) [C@H] (CC2) C6=CC (=O) OC6) [H]) [H]

Molecular Formula

C30H46O8

Molecular Weight

534.68

Storage Conditions

-20°C

Notes

For research use only.

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