Human VEGF R2 (Luc) HEK293 Reporter Cell
Human VEGF R2 (Luc) HEK293 Reporter Cell is expressed from Human HEK293.
Product Specifications
Background
Vascular endothelial growth factor (VEGF) is a potent angiogenic inducer that stimulates the expression of tissue factor (TF), the major cellular initiator of blood coagulation. VEGF could inhibit apoptosis and increase cellular proliferation. As the most abundant splice variant of VEGF-A, VEGF165 binds to the receptor tyrosine kinases, VEGFR1 and VEGFR2, leads to activation of the PI3K/AKT, p38 MAPK, FAK, and paxillin. Due to the angiogenesis ability of VEGF in cancer, interfering VEGF/VEGFR2 interaction has become an attractive method in cancer therapy.
Host
HEK293
Origin Species
Human
Target
VEGF R2
Tag
Luc
Applications
• Screen for anti-human VEGF R2 or anti-human VEGF neutralizing antibody. • Screen for human VEGF R2 small molecule inhibitor
Format
Liquid
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
Dry ice
Storage Conditions
Frozen in liquid nitrogen
Package Size
1Vial*2
Host or Source
HEK293
Species
Human
Curated Selection
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