MAL-di-EG-Val-Cit-PAB-MMAE
This product consists of the protease-cleavable linker MAL-di-EG-Val-Cit-PAB conjugated to the cytotoxic agent MMAE, forming a key component for constructing antibody-drug conjugates (ADCs) . It is widely used in ADC research for targeted cancer therapy, facilitating both in vitro cytotoxicity studies and in vivo efficacy evaluations in preclinical models.
Product Specifications
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
CC[C@H] (C) [C@@H] ([C@@H] (CC (N1[C@@H] (CCC1) [C@@H] ([C@@H] (C) C (N[C@H] (C) [C@@H] (O) C2=CC=CC=C2) =O) OC) =O) OC) N (C ([C@H] (C (C) C) NC ([C@H] (C (C) C) N (C (OCC3=CC=C (NC ([C@H] (CCCNC (N) =O) NC ([C@H] (C (C) C) NC (CCOCCOCCNC (CCN4C (C=CC4=O) =O) =O) =O) =O) =O) C=C3) =O) C) =O) =O) C
Molecular Formula
C72H112N12O18
Molecular Weight
1433.73
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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