THP-PEG4-Pyrrolidine (N-Me) -CH2OH
This PEG-based PROTAC linker, THP-PEG4-Pyrrolidine (N-Me) -CH2OH, is utilized in constructing bifunctional degraders such as PROTAC K-Ras Degrader-1. It serves as a critical spacer, connecting target-binding and E3 ligase-recruiting moieties to facilitate targeted protein degradation in cancer research, applicable for both in vitro and in vivo experimental studies.
Product Specifications
CAS Number
2378261-81-3
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
O (CCOCCOCCOCCOC1CCCCO1) [C@@H]2C[C@@H] (CO) N (C) C2
Molecular Formula
C19H37NO7
Molecular Weight
391.5
Storage Conditions
-20°C
Notes
For research use only.
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