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MC-Val-Cit-PAB-VX765

MC-VAL-CIT-PAB-VX765 is a derivative of the cathepsin-cleavable linker VX765, designed for conjugation to antibodies, polymers, or proteins to create targeted therapeutics. This ADC linker enables the specific release of payloads in lysosomes and is widely utilized in the research and development of antibody-drug conjugates for both in vitro and in vivo cancer studies.

Product Specifications

Field of Research

Signal Transduction

Smiles

O=C1C=CC (N1CCCCCC (N[C@H] (C (N[C@@H] (CCCNC (N) =O) C (NC2=CC=C (COC (NC3=CC=C (C (N[C@H] (C (N4CCC[C@H]4C (N[C@@H]5[C@H] (OCC) OC (C5) =O) =O) =O) C (C) (C) C) =O) C=C3Cl) =O) C=C2) =O) =O) C (C) C) =O) =O

Molecular Formula

C53H71ClN10O14

Molecular Weight

1107.66

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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