β-D-glucuronide-pNP-carbonate
β-D-Glucuronide-pNP-carbonate is a cleavable linker designed for antibody-drug conjugate (ADC) synthesis. Its β-glucuronidase-sensitive design enables targeted drug release, facilitating research into ADC efficacy and mechanism in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
894095-98-8
Product Name Alternative
Beta-D-glucuronide-pNP-carbonat, beta-D-glucuronide-pNP-carbonate, b-D-glucuronide-pNP-carbonate, βDglucuronidepNPcarbonate, β-D-glucuronide-pNP-carbonate, β D glucuronide pNP carbonate
Purity
99.78% (May vary between batches)
Solubility
DMSO:100 mg/mL (109.43 mM)
Smiles
C (OC (NCCC (NC1=C (O[C@H]2[C@H] (OC (C) =O) [C@@H] (OC (C) =O) [C@H] (OC (C) =O) [C@@H] (C (OC) =O) O2) C=CC (COC (OC3=CC=C (N (=O) =O) C=C3) =O) =C1) =O) =O) C4C=5C (C=6C4=CC=CC6) =CC=CC5
Molecular Formula
C45H43N3O18
Molecular Weight
913.83
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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