Palbociclib orotate
Palbociclib (PD 0332991) orotate is an orally bioavailable, selective CDK4/6 inhibitor (IC50: 11 and 16 nM, respectively) . It potently inhibits proliferation and induces cell cycle arrest in vitro and shows efficacy in vivo models, supporting research in HR+/HER2- breast cancer and hepatocellular carcinoma.
Product Specifications
CAS Number
2757498-64-7
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Molecular Formula
C29H33N9O6
Molecular Weight
603.63
Storage Conditions
-20°C
Notes
For research use only.
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