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Palbociclib orotate

Palbociclib (PD 0332991) orotate is an orally bioavailable, selective CDK4/6 inhibitor (IC50: 11 and 16 nM, respectively) . It potently inhibits proliferation and induces cell cycle arrest in vitro and shows efficacy in vivo models, supporting research in HR+/HER2- breast cancer and hepatocellular carcinoma.

Product Specifications

CAS Number

2757498-64-7

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Molecular Formula

C29H33N9O6

Molecular Weight

603.63

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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