HS148
HS148 is a potent and selective DAPK3 inhibitor (Ki=119 nM) . Its inhibition of DAPK3 activates the ULK1-dependent autophagy pathway, a mechanism shown to impede gastric cancer progression in research models. This compound is a valuable tool for studying autophagy, kinase signaling, and oncology in both cellular and animal studies.
Product Specifications
CAS Number
1892595-16-2
Product Name Alternative
DAPK3 inhibitor HS 148, DAPK3 inhibitor HS148, DAPK3 inhibitor HS-148, HS 148, HS-148
Field of Research
Cell Biology
Purity
98.02% (May vary between batches)
Solubility
DMSO:1.5 mg/mL (4.32 mM)
Smiles
O=C1N=C (SC (C (=O) N) CC) NC2=C1C=NN2C=3C=CC=C (F) C3
Molecular Formula
C15H14FN5O2S
Molecular Weight
347.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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