Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br
Glucocorticoid Receptor Agonist-1 Phosphate (Gly-Glu-Br) is a phosphate-containing linker-payload used in the construction of antibody-drug conjugates (ADCs) such as ABBV-154. It is applied in oncology research for developing targeted therapeutics, with its utility demonstrated in preclinical in vitro and in vivo studies for selective drug delivery.
Product Specifications
CAS Number
2344809-82-9
Field of Research
Pharmacology & Drug Discovery
Smiles
C (COP (=O) (O) O) (=O) [C@]12[C@]3 (C) [C@@] (C[C@]1 (O[C@H] (O2) C4=CC=C (CC5=CC (NC ([C@@H] (NC (CNC (CBr) =O) =O) CCC (O) =O) =O) =CC=C5) C=C4) [H]) ([C@]6 ([C@] ([C@@H] (O) C3) ([C@]7 (C) C (CC6) =CC (=O) C=C7) [H]) [H]) [H]
Molecular Formula
C44H51BrN3O14P
Molecular Weight
956.77
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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