Mal-PEG8-amide-Val-Ala- (4-NH2) -Exatecan
Mal-PEG8-amide-Val-Ala- (4-NH2) -Exatecan is a cleavable linker-payload used in constructing antibody-drug conjugates (ADCs) . It incorporates a topoisomerase I inhibitor derivative for targeted cytotoxicity, enabling research into ADC efficacy and mechanism in both in vitro and in vivo cancer models.
Product Specifications
CAS Number
2495742-34-0
Field of Research
Molecular Biology, Pharmacology & Drug Discovery
Smiles
O=C1N2C (C=3C (=C4C=5C (N3) =CC=C (NC ([C@@H] (NC ([C@@H] (NC (CCOCCOCCOCCOCCOCCOCCOCCOCCNC (CCN6C (=O) C=CC6=O) =O) =O) C (C) C) =O) C) =O) C5CCC4) C2) =CC7=C1COC (=O) [C@@]7 (CC) O
Molecular Formula
C57H77N7O18
Molecular Weight
1148.26
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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