Vc-PABC-DM1
Vc-PABC-DM1 is a small molecule linker-payload used in constructing antibody-drug conjugates (ADCs) with a cleavable disulfide linkage. It is specifically applied in ADC research to study linker stability in serum, a critical parameter for evaluating ADC efficacy and pharmacokinetics in both in vitro and in vivo models.
Product Specifications
CAS Number
1416792-90-9
Smiles
C[C@]12[C@@] (O1) ([C@H] (C) [C@@]3 (C[C@] (O) ([C@H] (OC) /C=C/C=C (\C) /CC4=CC (N (C) C (=O) C[C@@H]2OC ([C@@H] (N (C (CCSCC5=CC=C (NC ([C@@H] (NC ([C@H] (C (C) C) N) =O) CCCNC (N) =O) =O) C=C5) =O) C) C) =O) =C (Cl) C (OC) =C4) NC (=O) O3) [H]) [H]
Molecular Formula
C53H75ClN8O13S
Molecular Weight
1099.73
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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