Val-Ala-PABC-Exatecan
Val-Ala-PABC-Exatecan is a cleavable ADC linker-drug conjugate, combining the Tesirine linker with the cytotoxic payload Exatecan, a topoisomerase I inhibitor. It is a key component for constructing antibody-drug conjugates used in cancer research, enabling the study of targeted drug delivery in both in vitro and in vivo models.
Product Specifications
CAS Number
2845164-91-0
Field of Research
Molecular Biology, Pharmacology & Drug Discovery
Purity
99.52% (May vary between batches)
Smiles
N (C (OCC1=CC=C (NC ([C@@H] (NC ([C@H] (C (C) C) N) =O) C) =O) C=C1) =O) [C@@H]2C3=C4C (C=5N (C4) C (=O) C6=C (C5) [C@] (CC) (O) C (=O) OC6) =NC=7C3=C (CC2) C (C) =C (F) C7
Molecular Formula
C40H43FN6O8
Molecular Weight
754.80
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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