Val-Ala-PABC-Exatecan

Val-Ala-PABC-Exatecan is a cleavable ADC linker-drug conjugate, combining the Tesirine linker with the cytotoxic payload Exatecan, a topoisomerase I inhibitor. It is a key component for constructing antibody-drug conjugates used in cancer research, enabling the study of targeted drug delivery in both in vitro and in vivo models.

Product Specifications

CAS Number

2845164-91-0

Field of Research

Molecular Biology, Pharmacology & Drug Discovery

Purity

99.52% (May vary between batches)

Smiles

N (C (OCC1=CC=C (NC ([C@@H] (NC ([C@H] (C (C) C) N) =O) C) =O) C=C1) =O) [C@@H]2C3=C4C (C=5N (C4) C (=O) C6=C (C5) [C@] (CC) (O) C (=O) OC6) =NC=7C3=C (CC2) C (C) =C (F) C7