MC-VA-PABC-MMAE
MC-VA-PABC-MMAE is an antibody-drug conjugate (ADC) linker-payload module. It incorporates the potent tubulin polymerization inhibitor monomethyl auristatin E (MMAE), enabling targeted drug delivery. This module is widely used in ADC research for evaluating cytotoxicity in both in vitro and in vivo cancer models.
Product Specifications
CAS Number
1818864-51-5
Smiles
[C@H] ([C@H] (C (N[C@@H] ([C@@H] (O) C1=CC=CC=C1) C) =O) C) (OC) [C@]2 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC ([C@@H] (N (C (OCC3=CC=C (NC ([C@@H] (NC ([C@@H] (NC (CCCCCN4C (=O) C=CC4=O) =O) C (C) C) =O) C) =O) C=C3) =O) C) C (C) C) =O) [C@@H] (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC2) [H]
Molecular Formula
C65H99N9O14
Molecular Weight
1230.53
Storage Conditions
-20°C
Notes
For research use only.
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