Mal-PEG8-Val-Ala-PAB-Exatecan
This ADC linker, Mal-PEG8-Val-Ala-PAB-Exatecan, is designed to conjugate Nectin-4-targeting antibodies to the cytotoxic payload Exatecan. It enables the construction of investigational ADCs for targeted cancer therapy research, applicable in both in vitro and in vivo preclinical studies.
Product Specifications
CAS Number
2679821-39-5
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
N (C (OCC1=CC=C (NC ([C@@H] (NC ([C@@H] (NC (CCOCCOCCOCCOCCOCCOCCOCCOCCNC (CCN2C (=O) C=CC2=O) =O) =O) [C@H] (C) C) =O) C) =O) C=C1) =O) [C@@H]3C4=C5C (C=6N (C5) C (=O) C7=C (C6) [C@] (CC) (O) C (=O) OC7) =NC=8C4=C (CC3) C (C) =C (F) C8
Molecular Formula
C66H85FN8O20
Molecular Weight
1329.42
Storage Conditions
-20°C
Notes
For research use only.
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