Ac-Lys-Val-Cit-PABC-MMAE
This research compound is an antibody-drug conjugate (ADC) linker-drug complex, featuring the protease-cleavable Ac-Lys-Val-Cit-PABC peptide attached to the potent tubulin inhibitor monomethyl auristatin E (MMAE) . It is a key tool for developing and studying targeted cancer therapies in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1650569-89-3
Field of Research
Signal Transduction
Smiles
[C@H] ([C@H] (C (N[C@@H] ([C@@H] (O) C1=CC=CC=C1) C) =O) C) (OC) [C@]2 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC ([C@@H] (N (C (OCC3=CC=C (NC ([C@@H] (NC ([C@@H] (NC ([C@H] (CCCCN) NC (C) =O) =O) C (C) C) =O) CCCNC (N) =O) =O) C=C3) =O) C) [C@H] (C) C) =O) C (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC2) [H]
Molecular Formula
C66H108N12O14
Molecular Weight
1293.64
Storage Conditions
-20°C
Notes
For research use only.
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