MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan
MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan is an antibody-drug conjugate (ADC) linker-payload conjugate, combining a protease-cleavable peptide linker with the potent topoisomerase I inhibitor Exatecan. It is used in cancer research for developing ADCs, with applications in both in vitro cytotoxicity assays and in vivo xenograft studies to evaluate targeted tumor efficacy.
Product Specifications
CAS Number
2414393-22-7
Field of Research
Molecular Biology, Pharmacology & Drug Discovery
Smiles
N (C (=O) C1 (OCNC (CNC ([C@H] (CC2=CC=CC=C2) NC (CNC (CNC (CCCCCN3C (=O) C=CC3=O) =O) =O) =O) =O) =O) CCC1) [C@@H]4C5=C6C (C=7N (C6) C (=O) C8=C (C7) [C@] (CC) (O) C (=O) OC8) =NC=9C5=C (CC4) C (C) =C (F) C9
Molecular Formula
C55H60FN9O13
Molecular Weight
1074.12
Storage Conditions
-20°C
Notes
For research use only.
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