SC239
SC239 is a drug-linker conjugate for ADC development, combining the tubulin inhibitor SC209 with a cleavable Val-Cit-PABC linker and a DBCO group for site-specific conjugation. It demonstrates potent cytotoxicity in vitro, particularly in Igrov1 cells with low FolRα expression, supporting research into targeted cancer therapies.
Product Specifications
CAS Number
1977557-97-3
Smiles
C (CCC (N[C@H] (C (N[C@H] (C (NC1=CC=C (COC (NC2=CC (C ([C@@H] (C (N[C@H] (C (N ([C@H] (/C=C (/C (O) =O) \C) C (C) C) C) =O) [C@] (C) (C) C) =O) NC) (C) C) =CC=C2) =O) C=C1) =O) CCCNC (N) =O) =O) C (C) C) =O) (=O) N3C=4C (C#CC=5C (C3) =CC=CC5) =CC=CC4
Molecular Formula
C65H84N10O11
Molecular Weight
1181.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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