OH-Glu-Val-Cit-PAB-MMAE
OH-Glu-Val-Cit-PAB-MMAE is a key component for constructing antibody-drug conjugates (ADCs), combining a protease-cleavable linker with the cytotoxic agent MMAE. This construct is widely used in oncology research for developing targeted therapies, with applications in both in vitro cytotoxicity assays and in vivo xenograft studies.
Product Specifications
CAS Number
1895916-23-0
Field of Research
Signal Transduction
Smiles
[C@H] ([C@H] (C (N[C@@H] ([C@@H] (O) C1=CC=CC=C1) C) =O) C) (OC) [C@]2 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC ([C@@H] (N (C (OCC3=CC=C (NC ([C@@H] (NC ([C@@H] (NC (CCCC (O) =O) =O) [C@@H] (C) C) =O) CCCNC (N) =O) =O) C=C3) =O) C) C (C) C) =O) [C@H] (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC2) [H]
Molecular Formula
C63H100N10O15
Molecular Weight
1237.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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