Maytansinoid B
Maytansinoid B is a potent antimitotic cytotoxin used to construct antibody-drug conjugates (ADCs) . It functions by binding tubulin to disrupt microtubule dynamics, causing cell cycle arrest at the G2/M phase and inducing apoptosis. This mechanism is leveraged in both in vitro cytotoxicity assays and in vivo preclinical studies of targeted cancer therapies.
Product Specifications
CAS Number
1628543-40-7
Smiles
C[C@]12[C@@] (O1) ([C@H] (C) [C@@]3 (C[C@] (O) ([C@H] (OC) /C=C/C=C (\C) /CC4=CC (N (C) C (=O) C[C@@H]2OC ([C@@H] (N (C (CCNC) =O) C) C) =O) =C (Cl) C (OC) =C4) NC (=O) O3) [H]) [H]
Molecular Formula
C36H51ClN4O10
Molecular Weight
735.26
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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