SN38-COOH
SN38-COOH is the active metabolite of irinotecan, a topoisomerase I inhibitor that blocks DNA and RNA synthesis. It is a key payload for constructing antibody-drug conjugates (ADCs) and is widely used in cancer research for both in vitro cytotoxicity assays and in vivo efficacy studies.
Product Specifications
CAS Number
2170118-23-5
Smiles
O (C (CCC (O) =O) =O) [C@@]1 (CC) C2=C (C (=O) N3C (=C2) C=4C (C3) =C (CC) C=5C (N4) =CC=C (O) C5) COC1=O
Molecular Formula
C26H24N2O8
Molecular Weight
492.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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