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SN38-COOH

SN38-COOH is the active metabolite of irinotecan, a topoisomerase I inhibitor that blocks DNA and RNA synthesis. It is a key payload for constructing antibody-drug conjugates (ADCs) and is widely used in cancer research for both in vitro cytotoxicity assays and in vivo efficacy studies.

Product Specifications

CAS Number

2170118-23-5

Smiles

O (C (CCC (O) =O) =O) [C@@]1 (CC) C2=C (C (=O) N3C (=C2) C=4C (C3) =C (CC) C=5C (N4) =CC=C (O) C5) COC1=O

Molecular Formula

C26H24N2O8

Molecular Weight

492.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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