ZXH-4-130 TFA
ZXH-4-130 TFA is a heterobifunctional CRBN-VHL PROTAC that induces potent and selective degradation of its target. At 10 nM, it achieves around 80% CRBN degradation in MM1.S cells, providing a valuable chemical tool for targeted protein degradation research in oncology and molecular pharmacology.
Product Specifications
CAS Number
2711006-67-4
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
C (C (O) =O) (F) (F) F.O=C1C=2C (C (=O) N1C3C (=O) NC (=O) CC3) =CC=CC2OCCCCCCCCCCC (N[C@H] (C (=O) N4[C@H] (C (NCC5=CC=C (C=C5) C=6SC=NC6C) =O) C[C@@H] (O) C4) C (C) (C) C) =O
Molecular Formula
C48H59F3N6O11S
Molecular Weight
985.08
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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