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BSJ-03-204 triTFA

BSJ-03-204 triTFA is a Cereblon- and CDK-targeted PROTAC that potently degrades CDK4/6 with IC50 values of 26.9 nM and 10.4 nM, respectively, while sparing IKZF1/3. This selective degrader is a valuable chemical probe for studying CDK4/6-dependent cancers in both cellular and in vivo models, demonstrating anti-proliferative activity.

Product Specifications

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Molecular Formula

C49H51F9N10O14

Molecular Weight

1174.97

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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