SJ995973
SJ995973 is a potent and selective BET PROTAC degrader. It induces targeted degradation of BET proteins, demonstrating robust anti-proliferative activity in cancer cell lines and promising efficacy in xenograft models, making it a valuable chemical probe for oncology and epigenetics research.
Product Specifications
CAS Number
2882065-25-8
Product Name Alternative
PROTAC, SJ 995973, SJ-995973
Field of Research
Pharmacology & Drug Discovery
Purity
99.36% (May vary between batches)
Solubility
DMSO:80 mg/mL (109.55 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (4.52 mM)
Smiles
CC=1C2=C (N3C ([C@H] (CC (NCCCCCNC (COC4=CC=C (C=C4) C5C (=O) NC (=O) CC5) =O) =O) N=C2C6=CC=C (Cl) C=C6) =NN=C3C) SC1C
Molecular Formula
C37H40ClN7O5S
Molecular Weight
730.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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