PhosTAC7

PhosTAC7 is a heterobifunctional molecule that induces targeted dephosphorylation of FOXO3a at serine 318 by recruiting the phosphatase PP2A. This PROTAC-based degrader enables the study of FOXO3a signaling and its role in cellular processes such as apoptosis and metabolism in both in vitro and in vivo research models.

Product Specifications

CAS Number

3016307-75-5

Field of Research

Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Purity

98.96% (May vary between batches)

Smiles

[C@H] (C (=O) N1[C@H] (C (O[C@H] (CCC2=CC (OC) =C (OC) C=C2) C3=CC (OCC (NCCOCCOCCOCCOCCOCCOCCOCCCCCCCl) =O) =CC=C3) =O) CCCC1) (CC) C4=CC (OC) =C (OC) C (OC) =C4