JPS016 TFA
JPS016 is a benzamide-based VHL-recruiting PROTAC that induces potent degradation of class I HDACs, specifically HDAC1 and HDAC2. This degradation leads to altered gene expression and enhanced apoptosis in cellular models like HCT116, supporting its use as a chemical probe for oncology and epigenetics research.
Product Specifications
Field of Research
Epigenetics & Chromatin, Immunology & Inflammation, Molecular Biology, Pharmacology & Drug Discovery
Molecular Formula
C50H64F3N7O10S
Molecular Weight
1012.14
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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