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Thalidomide-NH-C10-NH2 hydrochloride

This thalidomide-based cereblon ligand, provided as a hydrochloride salt, serves as a key building block for constructing PROTAC degraders. It enables the recruitment of the CRBN E3 ubiquitin ligase for targeted protein degradation, a tool widely used in both in vitro and in vivo proteolysis research.

Product Specifications

CAS Number

2460022-53-9

Field of Research

Pharmacology & Drug Discovery

Smiles

Cl.O=C1NC (=O) C (N2C (=O) C=3C=CC=C (NCCCCCCCCCCN) C3C2=O) CC1

Molecular Formula

C23H33ClN4O4

Molecular Weight

464.99

Storage Conditions

-20°C

Notes

For research use only.

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