PD-L1-IN-2

PD-L1-IN-2 is a Naamidine J-derived small molecule that acts as an antineoplastic immunomodulator by inhibiting PD-L1 activity. In vivo research demonstrates it downregulates PD-L1 expression and enhances T-cell infiltration in tumors, showing promise for immunooncology studies, particularly in colorectal cancer models.