HIF-1α-IN-2 hydrochloride

HIF-1α-IN-2 hydrochloride is a potent, small molecule inhibitor of HIF-1α with demonstrated anticancer activity in vitro, showing IC50 values of 28 nM and 15 nM in MDA-MB-231 and MiaPaCa-2 cell lines, respectively. It functions by suppressing both the transcription and translation of HIF-1α, making it a valuable tool for researching hypoxia signaling pathways in cancer biology.