PVZB1194
PVZB1194 is a biphenyl-type, ATP-competitive inhibitor of the mitotic kinesin Eg5 (KIF11), binding its α4/α6 allosteric pocket to suppress ATPase activity. This mechanism induces cell cycle arrest and apoptosis, demonstrating its utility for anticancer research in both cellular and biochemical assays.
Product Specifications
CAS Number
1141768-04-8
Field of Research
Signal Transduction
Smiles
O=S (=O) (N) C1=CC=C (C=C1) C=2C=CC (=C (F) C2) C (F) (F) F
Molecular Formula
C13H9F4NO2S
Molecular Weight
319.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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