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NH2-UAMC1110 TFA

NH2-UAMC1110 TFA is a modified derivative of the potent and selective fibroblast activation protein (FAP) inhibitor UAMC1110, featuring an aminobutoxy linker for conjugation in the synthesis of FAPI-QS tracers. It exhibits low nanomolar inhibition of FAP and related dipeptidyl peptidases (DPP4, DPP9, DPPII, and PREP), making it a valuable tool for in vitro and in vivo cancer research, particularly in the development of targeted imaging and therapeutic agents.

Product Specifications

CAS Number

2990021-73-1

Product Name Alternative

FAP

Field of Research

Immunology & Inflammation

Purity

99.02% (May vary between batches)

Solubility

H2O:200 mg/mL (366.66 mM)

Smiles

C (C (O) =O) (F) (F) F.C (NCC (=O) N1[C@H] (C#N) CC (F) (F) C1) (=O) C=2C3=C (C=CC (OCCCCN) =C3) N=CC2

Molecular Formula

C23H24F5N5O5

Molecular Weight

545.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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