JAK-IN-26
JAK-IN-26 is a potent, orally bioavailable small molecule inhibitor of Janus kinase (JAK) . It effectively suppresses IFN-α2B-induced STAT3 phosphorylation in Jurkat cells with an IC50 of 17.2 nM. This compound is a valuable research tool for investigating JAK-STAT signaling in autoimmune, inflammatory, and oncological contexts, both in vitro and in vivo.
Product Specifications
CAS Number
2417134-93-9
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
O=C (NC1=NC=C (C (=O) CC) C (=C1) NC2=CC=CC (C=3N=CN (N3) C) =C2OC) C4CC4
Molecular Formula
C22H24N6O3
Molecular Weight
420.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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