Skp2 inhibitor 2
Skp2 inhibitor 2 (14f) is a small molecule that selectively targets the Skp2-Cks1 complex with an IC50 of 10.2 μM. By inhibiting this F-box protein, it modulates Skp2 SCF ubiquitin ligase activity, providing a research tool for studying cell cycle regulation, oncogenesis, and protein degradation pathways in both cellular and biochemical assays.
Product Specifications
CAS Number
2760612-77-7
Field of Research
Pharmacology & Drug Discovery; Cell Biology, Protein Biochemistry
Smiles
O=C (NCC1CCN (C2=NC (C3=CC=CC=C3) =C (N=C2) C=4C=CC=CC4) CC1) C (C) (C) C
Molecular Formula
C27H32N4O
Molecular Weight
428.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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