NSC194598
NSC194598 is a potent small molecule inhibitor of p53 DNA-binding activity, exhibiting an IC50 of 180 nM in vitro. It is used in research to study radiation and chemotherapy-induced acute toxicity in normal tissues and has been shown to inhibit mutated RET gene transcription in medullary thyroid carcinoma models.
Product Specifications
CAS Number
5358-76-9
Field of Research
Cell Biology, Signal Transduction
Smiles
O=N=1C (=NC2=CC=CC=3C=4C=CC=CC4C1C23) CN5CCCCC5
Molecular Formula
C20H19N3O
Molecular Weight
317.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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