Nedometinib
Nedometinib (NFX-179) is a selective MEK1 inhibitor that suppresses the MAPK pathway, demonstrating dose-dependent inhibition of human squamous cell carcinoma growth in vitro. Its research applications include studying oncogenic signaling in skin malignancies and evaluating antitumor efficacy in preclinical models.
Product Specifications
CAS Number
2252314-46-6
Product Name Alternative
MEK1, NFX 179, NFX179, NFX-179
Field of Research
Cell Biology, Signal Transduction
Purity
99.18% (May vary between batches)
Solubility
DMSO:80 mg/mL (170.13 mM)
Smiles
O=C (NOCCO) C=1C=2C=CC=NC2N (C1NC3=CC=C (I) C=C3F) C
Molecular Formula
C17H16FIN4O3
Molecular Weight
470.24
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
765760 1 L
1- Propanol for Pesticide residue analysis (n-Propyl Alcohol , Propan-1-Ol)
Sign In for Pricing
View Details 
FEK0938-carrier-free 96 Well With Removable Strips
Mouse Angiopoietin-2 PicoKine® Quick ELISA Kit, Carrier-free
Sign In for Pricing
View Details 
bs-6612R-PE-Cy7 100 µL
BMP15 Polyclonal Antibody, PE-Cy7 Conjugated
Sign In for Pricing
View Details