Nedometinib
Nedometinib (NFX-179) is a selective MEK1 inhibitor that suppresses the MAPK pathway, demonstrating dose-dependent inhibition of human squamous cell carcinoma growth in vitro. Its research applications include studying oncogenic signaling in skin malignancies and evaluating antitumor efficacy in preclinical models.
Product Specifications
CAS Number
2252314-46-6
Product Name Alternative
MEK1, NFX 179, NFX179, NFX-179
Field of Research
Cell Biology, Signal Transduction
Purity
99.18% (May vary between batches)
Solubility
DMSO:80 mg/mL (170.13 mM)
Smiles
O=C (NOCCO) C=1C=2C=CC=NC2N (C1NC3=CC=C (I) C=C3F) C
Molecular Formula
C17H16FIN4O3
Molecular Weight
470.24
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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