NUC-7738
NUC-7738 is a phosphoramidate prodrug of 3'-deoxyadenosine designed to overcome resistance mechanisms. It inhibits β-catenin signaling by reducing its nuclear expression in AML cells, showing potential for cancer research in both in vitro and in vivo models.
Product Specifications
CAS Number
2348493-39-8
Product Name Alternative
NUC7738
Purity
97.32% (May vary between batches)
Solubility
DMSO:80 mg/mL (140.72 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.8 mM)
Smiles
O[C@H]1[C@H] (N2C=3C (N=C2) =C (N) N=CN3) O[C@H] (COP (OC4=CC=CC=C4) (N[C@H] (C (OCC5=CC=CC=C5) =O) C) =O) C1
Molecular Formula
C26H29N6O7P
Molecular Weight
568.52
Storage Conditions
-20°C
Notes
For research use only.
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