GNE-7883
GNE-7883 is a small molecule TEAD inhibitor that suppresses YAP/TAZ oncogenic signaling. It is a valuable research tool for investigating Hippo pathway-dependent cancers in both cellular and animal models, demonstrating efficacy in reducing tumor cell proliferation.
Product Specifications
CAS Number
2648450-42-2
Product Name Alternative
GNE 7883, GNE7883, YAP, TEAD
Field of Research
Stem Cell & Developmental Biology
Purity
97.61% (May vary between batches)
Solubility
DMSO:30 mg/mL (59.93 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4 mM)
Smiles
O=C1C=C (NC2=C (C (=O) N3CC (CF) C3) C (=NN12) C=4N=CC=NC4C) C=5C=CC (=CC5) C6CCCCC6
Molecular Formula
C28H29FN6O2
Molecular Weight
500.57
Storage Conditions
-20°C
Notes
For research use only.
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