Anti-Interleukin-21 Receptor (IL-21R) (ED) Antibody

Rabbit Polyclonal Antibody specific to IL-21R (ED)

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

IL-21 receptor, IL-21R, Novel interleukin receptor, CD antigen CD360

Gene Name

IL21R

NCBI Gene ID

UniProt

Q9HBE5

Cellular Locus

Membrane; Single-pass type I membrane protein.

Host

Rabbit

Reactivity

Human

Immunogen

Peptide corresponding to aa 97-111 of human IL-21R precursor.

Target Antigen

Interleukin-21 receptor

Target

Interleukin-21 Receptor (IL-21R) (ED)

Clonality

Polyclonal

Type

Antibody

Applications

ELISA, WB, IHC-P, IF

Field of Research

Growth Factors, Cytokines, Receptors

Purification Method

Purified by peptide immuno-affinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium that is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Phosphate Buffered Saline

Function

This is a receptor for interleukin-21.

Additionnal Information

Immunoblotting: use at 0.5-1 ug/mL. In immunoblots, a band of 60 kD is detected. <br><br>Positive control: Raji cell lysate.

Storage Conditions

This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.

Specificity

This antibody recognizes human IL- 21R, the receptor for IL-21. IL-21R complexes with the common cytokine receptor g chain, gc, and mediates IL-21 signaling. IL-21 and its receptor activate the JAK-STAT signaling pathway. IL-21R is expressed in spleen and thymus as well as on natural killer (NK), T and B cells and plays a role in the proliferation and maturation of these cell populations.