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A011

A011 is a potent and selective ATM kinase inhibitor with an IC50 of 1.0 nM. In research, it induces apoptosis and G2/M arrest when combined with CPT-11 (irinotecan), demonstrating antitumor efficacy in both cellular and in vivo models.

Product Specifications

Field of Research

Cell Biology, Molecular Biology, Signal Transduction

Molecular Formula

C27H28N6O

Molecular Weight

452.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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