HCAIX/VII-IN-1

HCAIX/VII-IN-1 is a potent and selective small molecule inhibitor of human carbonic anhydrase isoforms VII and IX, with Ki values of 35.6 nM and 28.0 nM, respectively. Its application is relevant in cancer research, targeting tumor-associated CAIX, and in neurological disease studies, focusing on brain-expressed CAVII, supporting both in vitro and in vivo experimental models.